Biomaterial Database

The nose, minor salivary glands, and sarcoidosis. 1984

D Postma, and T L Fry, and B T Malenbaum

Fifty-nine patients referred to the ear, nose, and throat clinic for random minor salivary gland (MSG) biopsy were studied. After a careful head and neck examination, a random MSG biopsy and a random inferior turbinate or specific nasal lesion biopsy was done. Of 30 patients with bilateral hilar lymphadenopathy (BHL), 12 of 26 who were thought to have sarcoidosis had abnormal findings on MSG biopsy. Of 29 patients without BHL, none of the six who were later believed to have sarcoidosis had abnormal findings on MSG biopsy. The other 23 patients without BHL and who later were believed findings on MSG biopsy. A careful history, physical examination, and chest roentgenogram should precede referral for random MSG biopsy. Patients without BHL and without other evidence for systemic sarcoidosis do not benefit from random MSG biopsies. This is especially true because of the relative nonspecificity of the finding of a noncaseating granuloma.

UI	MeSH Term	Description	Entries
D008206	Lymphatic Diseases	Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.	Lymphatism,Status Lymphaticus,Disease, Lymphatic,Diseases, Lymphatic,Lymphatic Disease
D009297	Nasal Mucosa	The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells.	Nasal Epithelium,Schneiderian Membrane,Epithelium, Nasal,Membrane, Schneiderian,Mucosa, Nasal
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001706	Biopsy	Removal and pathologic examination of specimens from the living body.	Biopsies
D012469	Salivary Glands	Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).	Gland, Salivary,Glands, Salivary,Salivary Gland
D012470	Salivary Glands, Minor	Accessory salivary glands located in the lip, cheek, tongue, floor of mouth, palate and intramaxillary.	Gland, Minor Salivary,Glands, Minor Salivary,Minor Salivary Gland,Minor Salivary Glands,Salivary Gland, Minor
D012507	Sarcoidosis	An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.	Besnier-Boeck Disease,Boeck's Sarcoid,Besnier-Boeck-Schaumann Syndrome,Boeck Disease,Boeck's Disease,Schaumann Disease,Schaumann Syndrome,Schaumann's Syndrome,Besnier Boeck Disease,Besnier Boeck Schaumann Syndrome,Boeck Sarcoid,Boecks Disease,Boecks Sarcoid,Disease, Schaumann,Sarcoid, Boeck's,Sarcoidoses,Schaumann's Syndromes,Syndrome, Besnier-Boeck-Schaumann,Syndrome, Schaumann,Syndrome, Schaumann's