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The production of vitamin D metabolites in response to ultraviolet irradiation has been studied in 5 control subjects and 8 patients with psoriasis; both groups responded similarly. Significant increases within the normal range were observed for serum 1,25-dihydroxyvitamin D; these increases were negatively related to the initial concentrations of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D. Serum 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D increased linearly over the 21 days of study, the production of 25-hydroxyvitamin D being negatively correlated with its own initial concentration. The changes in vitamin D metabolism were accompanied by significant rises within the normal ranges in serum inorganic phosphorus and in urinary calcium. These results indicate the variation of 1,25-dihydroxyvitamin D occurs in vitamin-D-replete adults and that this variation is probably responsible for the observed alterations in calcium and phosphorus metabolism.
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
January 1981,
Calcified tissue international,
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
April 1995,
Annals of internal medicine,
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
February 1980,
American journal of diseases of children (1960),
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
June 2012,
Clinical biochemistry,
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
March 1982,
Ugeskrift for laeger,
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
February 1979,
The New England journal of medicine,
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
July 1982,
Calcified tissue international,
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
October 1988,
BMJ (Clinical research ed.),
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
September 1983,
The Journal of pediatrics,
E B Mawer, and
J L Berry, and
E Sommer-Tsilenis, and
W Beykirch, and
A Kuhlwein, and
B T Rohde
April 1981,
Biochemical and biophysical research communications,
