Biomaterial Database

Comparison of the immunogenicity of Newcastle disease virus strains V4, B1 and La Sota in chickens. 1. Tests in susceptible chickens. 1984

H A Westbury

The immunogenicity of the Australian Newcastle disease virus (NDV) strain V4 was compared with that of the International reference preparation of Hitchner B1 and a commercial La Sota strain. Immunity was assessed serologically using the log mean HI titres 21 days after immunisation, the percentage of birds in each group which developed titres greater than 2(3) and their resistance to graded challenge doses of the virulent Herts 33/56 strain of NDV. These tests showed that the V4 strain was significantly less immunogenic (P less than 0.01) than the B1 or La Sota strains when administered intraocularly (eye drop) or by aerosol methods. When given in the drinking water V4 induced a better immunity (P less than 0.01) than the B1 strain in one of 2 experiments.

UI	MeSH Term	Description	Entries
D009521	Newcastle Disease	An acute febrile, contagious, viral disease of birds caused by an AVULAVIRUS called NEWCASTLE DISEASE VIRUS. It is characterized by respiratory and nervous symptoms in fowl and is transmissible to man causing a severe, but transient conjunctivitis.	Disease, Newcastle
D009522	Newcastle disease virus	The most well known avian paramyxovirus in the genus AVULAVIRUS and the cause of a highly infectious pneumoencephalitis in fowl. It is also reported to cause CONJUNCTIVITIS in humans. Transmission is by droplet inhalation or ingestion of contaminated water or food.	Avian Paramyxovirus 1,Paramyxovirus 1, Avian
D011201	Poultry Diseases	Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.	Disease, Poultry,Diseases, Poultry,Poultry Disease
D002645	Chickens	Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.	Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000914	Antibodies, Viral	Immunoglobulins produced in response to VIRAL ANTIGENS.	Viral Antibodies
D014611	Vaccination	Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.	Immunization, Active,Active Immunization,Active Immunizations,Immunizations, Active,Vaccinations