Compatibility between psychophysical and physiological measurements of aural combination tones. 1978

J L Goldstein, and G Buchsbaum, and M Furst

Neural studies of combination-tone (CT) responses in the eighth nerve and antroventral cochlear nucleus of anesthetized cats give evidence of stimuluslike intracochlear CT's with a similar amplitude spectrum as inferred from human psychophysics. An unsolved problem raised in these studies is the gross discrepency between the phase of CT's measured psychophysically and neurally. It is unknown whether incompatibility lies in the cochleas or the criteria for measuring CT's in the different experiments. New psychophysical experiments were developed to clarify this issue. Secondary CT's (SCT) were generated by the interaction between a primary cubic CT (CTT) and a third tone in the stimulus. The SCT measured by cancellation exhibits similar properties to those of a CT generated by the comparable two-tone stimulus. The SCT is eliminated when the CCT is cancelled. These findings support the view that CT's exist in the cochlea as spatially distinct, stimuluslike excitations, and that CT excitations are eliminated by psychophysical cancellation. The SCT phase provides a measure of the CCT phase without requiring direct cancellation of the CCT. Phase measurements by the new indirect and older direct methods imply that the CT phase may be constant with changing sound level of the primary stimulus as found in the neural studies; these measurements also reveal nonlinear phase effects not found in neural studies. The new data suggest that the CT phase discrepancy may be caused by a real difference between the nonlinear mechanisms in the alert humans and anesthetized cats, and provide new constraints for clarifying this issue through further study.

UI MeSH Term Description Entries
D010897 Pitch Discrimination The ability to differentiate sound frequency or pitch. Discrimination, Pitch,Pitch Discriminations
D011601 Psychophysics The science dealing with the correlation of the physical characteristics of a stimulus, e.g., frequency or intensity, with the response to the stimulus, in order to assess the psychologic factors involved in the relationship. Psychophysic
D011603 Psychophysiology The study of the physiological basis of human and animal behavior. Mind-Body Relations (Physiology),Psychology, Physiological,Mind-Body Relationship (Physiology),Physiologic Psychology,Physiological Psychology,Psychology, Physiologic,Mind Body Relations (Physiology),Mind Body Relationship (Physiology),Mind-Body Relation (Physiology),Mind-Body Relationships (Physiology),Physiologic Psychologies,Psychologies, Physiologic,Relation, Mind-Body (Physiology),Relations, Mind-Body (Physiology),Relationship, Mind-Body (Physiology),Relationships, Mind-Body (Physiology)
D003051 Cochlea The part of the inner ear (LABYRINTH) that is concerned with hearing. It forms the anterior part of the labyrinth, as a snail-like structure that is situated almost horizontally anterior to the VESTIBULAR LABYRINTH. Cochleas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000159 Vestibulocochlear Nerve The 8th cranial nerve. The vestibulocochlear nerve has a cochlear part (COCHLEAR NERVE) which is concerned with hearing and a vestibular part (VESTIBULAR NERVE) which mediates the sense of balance and head position. The fibers of the cochlear nerve originate from neurons of the SPIRAL GANGLION and project to the cochlear nuclei (COCHLEAR NUCLEUS). The fibers of the vestibular nerve arise from neurons of Scarpa's ganglion and project to the VESTIBULAR NUCLEI. Cranial Nerve VIII,Eighth Cranial Nerve,Cochleovestibular Nerve,Statoacoustic Nerve,Cochleovestibular Nerves,Cranial Nerve VIIIs,Cranial Nerve, Eighth,Cranial Nerves, Eighth,Eighth Cranial Nerves,Nerve VIIIs, Cranial,Nerve, Cochleovestibular,Nerve, Eighth Cranial,Nerve, Statoacoustic,Nerve, Vestibulocochlear,Nerves, Cochleovestibular,Nerves, Eighth Cranial,Nerves, Statoacoustic,Nerves, Vestibulocochlear,Statoacoustic Nerves,VIIIs, Cranial Nerve,Vestibulocochlear Nerves
D000161 Acoustic Stimulation Use of sound to elicit a response in the nervous system. Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D001309 Auditory Threshold The audibility limit of discriminating sound intensity and pitch. Auditory Thresholds,Threshold, Auditory,Thresholds, Auditory

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