[Ultrastructure of eruptive capillary hemangioma (granuloma pyogenicum sive teleangiectaticum)]. 1984

W C Marsch

Twelve lesions of so-called granuloma pyogenicum of the skin were examined by electron microscopy. The process is initially characterized by a solid proliferation of endothelial cells. The lumen is formed by a distention of the intercellular space and by invaginations of the cytoplasmic membrane. Even the walls of greatly ectatic vessels are only lined by endothelial cells, which is an indication for their capillary nature. Weibel-Palade bodies are rare. The basal lamina is born in the process of lumen formation and flattening of the endothelial cells. Cytoplasmic blebs on endothelial cell surfaces represent aqueous compartments. Their appearance probably results from a lack of energy supply due to an insufficient microcirculation. Exulceration of the epifocal epidermis is definitely a secondary event and leads to direct contact of the capillary vascular tissue with living and nonliving agents in the environment. This induces a strong acute inflammatory response, which results in fibrin exudation and emigration of neutrophilic granulocytes. The lesion is a benign vascular tumour. Therefore the term "eruptive capillary hemangioma" is justified.

UI MeSH Term Description Entries
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D002196 Capillaries The minute vessels that connect arterioles and venules. Capillary Beds,Sinusoidal Beds,Sinusoids,Bed, Sinusoidal,Beds, Sinusoidal,Capillary,Capillary Bed,Sinusoid,Sinusoidal Bed
D004727 Endothelium A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body. Endotheliums
D006391 Hemangioma A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000) Angioma,Chorioangioma,Hemangioma, Histiocytoid,Hemangioma, Intramuscular,Chorangioma,Chorangiomas,Chorioangiomas,Hemangiomas,Hemangiomas, Histiocytoid,Hemangiomas, Intramuscular,Histiocytoid Hemangioma,Histiocytoid Hemangiomas,Intramuscular Hemangioma,Intramuscular Hemangiomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012867 Skin The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D012878 Skin Neoplasms Tumors or cancer of the SKIN. Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm

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