BIOMAT Database Logo BIOMAT Database Logo

Ovarian and adrenal vein steroids in healthy women with ovulatory cycles--selective catheterization findings. 1984

L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein

Bilateral ovarian-adrenal vein catheterization and androgen measurements in the efferent samples were utilized to directly assess glandular steroid release in 8 healthy volunteers with proven ovulatory cycles during the early follicular phase. Side effects did not occur in any of the women. Hormone levels were as follows (mean +/- SD; ng/ml) T: peripheral vein (PV) 0.36 +/- 0.16, ovarian veins (OV) 0.39 +/- 0.13, adrenal veins (AV) 0.85 +/- 0.63; dihydro-T (DHT): PV 0.25 +/- 0.09, OV 0.29 +/- 0.10, AV 0.93 +/- 0.65; delta 4-androstendione (A): PV 0.88 +/- 0.34, OV 1.82 +/- 1.04, AV 9.22 +/- 8.04; DHEA; PV 5.13 +/- 1.96, OV 6.73 +/- 2.69, AV 146.79 +/- 217.24; DS PV 1860 +/- 850, OV 1937 +/- 1039, AV 2567 +/- 1201; 17 alpha-hydroxyprogesterone (17P): PV 0.60 +/- 0.19, OV 1.46 +/- 1.64, AV 6.94 +/- 6.20; F: PV 170 +/- 50, OV 130 +/- 21, AV 788 +/- 1320; the bilateral differences of effluent levels were not significant. Glandular-peripheral vein steroid gradients served as semiquantitative estimates of momentary secretory activity; they were as follows (mean +/- SD; ng/ml) T: ovarian-peripheral vein gradient (OPG) 0.03 +/- 0.09, adrenal-peripheral vein gradient (APG) 0.48 +/- 0.57; DHT: OPG 0.05 +/- 0.05, APG 0.69 +/- 0.60; A: OPG 0.97 +/- 1.13, APG 8.33 +/- 7.86; DHEA: OPG 1.70 +/- 1.80, APG 141.80 +/- 216.60; DS: OPG 191 +/- 72, APG 706 +/- 824; 17P: OPG 0.87 +/- 1.67, APG 6.30 +/- 6.10; F: OPG 38 +/- 11, APG 610 +/- 1329. Gradient, analysis revealed that the ovaries produced significant quantities of A, DHEA and 17P, but no T, DHT or F between day 3-7 of the cycle; direct gonadal DS output was detected in 2 individuals. A significant OPG for DS was detected in two individuals possibly indicating its partially gonadal origin. The adrenals released larger amounts of A, DHEA and 17P than the ovaries at this stage (P less than 0.05); also, they consistently secreted T, DHT, DS and F.

UI MeSH Term Description Entries
D010053 Ovary The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE. Ovaries
D010060 Ovulation The discharge of an OVUM from a rupturing follicle in the OVARY. Ovulations
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002404 Catheterization Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions. Cannulation,Cannulations,Catheterizations
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006908 Hydroxyprogesterones Metabolites or derivatives of PROGESTERONE with hydroxyl group substitution at various sites.
D000311 Adrenal Glands A pair of glands located at the cranial pole of each of the two KIDNEYS. Each adrenal gland is composed of two distinct endocrine tissues with separate embryonic origins, the ADRENAL CORTEX producing STEROIDS and the ADRENAL MEDULLA producing NEUROTRANSMITTERS. Adrenal Gland,Gland, Adrenal,Glands, Adrenal
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000728 Androgens Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power. Androgen,Androgen Receptor Agonist,Androgen Effect,Androgen Effects,Androgen Receptor Agonists,Androgenic Agents,Androgenic Compounds,Agents, Androgenic,Agonist, Androgen Receptor,Agonists, Androgen Receptor,Compounds, Androgenic,Effect, Androgen,Effects, Androgen,Receptor Agonist, Androgen,Receptor Agonists, Androgen

Related Publications

L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Differential ovarian and adrenal vein catheterization.
August 1976, American journal of obstetrics and gynecology,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Adrenal and ovarian vein androgen levels and laparoscopic findings in hirsute women.
May 1975, American journal of obstetrics and gynecology,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Diagnostic evaluation of hirsutism in women by selective bilateral adrenal and ovarian venous catheterization.
September 1978, Fertility and sterility,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Ovarian stimulation for disordered ovulatory cycles.
March 1987, Asia-Oceania journal of obstetrics and gynaecology,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Combined ovarian and adrenal vein catheterization to determine the site(s) of androgen overproduction in hirsute women.
August 1971, The Journal of clinical endocrinology and metabolism,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
[On patients with premature ovarian failure, restoring ovulatory cycles].
February 1988, Nihon Sanka Fujinka Gakkai zasshi,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Lifetime number of ovulatory cycles and epithelial ovarian cancer risk in African American women.
May 2017, Cancer causes & control : CCC,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Ovulatory disorders and infertility in women with regular menstrual cycles.
June 1990, Current opinion in obstetrics & gynecology,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Gonadotropin, steroid, and inhibin levels in women with incipient ovarian failure during anovulatory and ovulatory rebound cycles.
January 1991, The Journal of clinical endocrinology and metabolism,
L Moltz, and R Sörensen, and U Schwartz, and J Hammerstein
Adrenal- and ovarian-vein steroids and LH response to GnRH in two patients with virilizing adrenocortical adenoma studied by selective catheterizations.
January 1992, Hormone research,
Copied contents to your clipboard!