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Hypertension is a frequent complication of reflux nephropathy. The cause of this hypertension is unknown. Our study was undertaken to assess the possible role of the renin-angiotensin system in the hypertension associated with unilateral reflux nephropathy. We selected for study 17 normotensive and 12 hypertensive patients with strictly unilateral reflux nephropathy. There were 3 normotensive and 2 hypertensive patients with a renal vein renin ratio exceeding 1.5. Of these 3 normotensive patients 1 had evidence from divided renal function studies to suggest functional renal ischemia. No consistent evidence was obtained to support the concept that the renin-angiotensin system has a primary role in the non-malignant hypertension of unilateral reflux nephropathy.
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
March 1986,
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R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
November 1980,
Urology,
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
January 1994,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
May 1988,
Japanese circulation journal,
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
December 1971,
Ugeskrift for laeger,
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
May 1976,
Urology,
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
September 1972,
Lancet (London, England),
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
February 1973,
Nihon Jinzo Gakkai shi,
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
December 1975,
The Journal of laboratory and clinical medicine,
R R Bailey, and
C U McRae, and
T M Maling, and
G Tisch, and
P J Little
November 1968,
Archives of internal medicine,
