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In 36 patients, intraoperative peritoneal lavage with PVP-iodine solution (26 patients) or with the iodine free chemotherapeutic agent Taurolin (10 patients) was performed because of peritonitis. Total iodine serum levels increased considerably after peritoneal lavage with PVP-iodine. In the early postoperative phase, the resorbed iodine was mostly present as iodide in serum. Iodine serum values returned to normal after 30 days. A decrease in T4 and T3 could be observed with a concomitant reciprocal increase of rT3 in the acute phase of peritonitis. Normalization of the thyroid hormone took place after 8 days. A stronger increase in T4 occurred temporarily in 2 of 5 patients known to have thyroid function disorders. These changes in thyroid hormone may also be considered as the consequence of the severe primary disease. Normalization of hormone values was clearly delayed after PVP iodine lavage. The possible risk of an iodine-induced thyrotoxicosis after intraperitoneal application of PVP-iodine is pointed out, and objections are made to using this therapy.
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
July 1981,
Surgery, gynecology & obstetrics,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
December 1971,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
May 1983,
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
January 1970,
Acta chirurgica Scandinavica,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
January 1976,
Annales chirurgiae et gynaecologiae. Supplementum,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
January 1976,
Annales chirurgiae et gynaecologiae,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
October 1975,
International surgery,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
January 1980,
Acta chirurgica Iugoslavica,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
August 1972,
Harefuah,
G Görtz, and
R Häring, and
M Henckel, and
H Meinhold
August 2002,
Wiener klinische Wochenschrift,
