Correlations between human skin bacteria and skin lipids. 1984

J N Kearney, and E Ingham, and W J Cunliffe, and K T Holland

Correlation matrices were constructed for various human skin variables (propionibacteria, micrococcaceae, sebum excretion rate, percentage of free fatty acids and free fatty acid production rate). Two independent populations were studied (n = 87 and n = 103), and a subpopulation (n = 30) was investigated on three occasions at intervals of I month. In this way consistently high correlations could be differentiated from 'fortuitous' correlations. Propionibacteria versus micrococcaceae showed the highest correlation coefficient and propionibacteria versus percentage free fatty acids was also highly correlated. A scatter diagram indicated a relationship between the lower threshold of microbial density and sebum excretion rate. An explanation based on relative duct and gland size is presented.

UI MeSH Term Description Entries
D008297 Male Males
D008835 Micrococcaceae A family of bacteria ranging from free living and saprophytic to parasitic and pathogenic forms.
D011423 Propionibacteriaceae A family of gram-positive bacteria found in dairy products or in the intestinal tracts of animals.
D005230 Fatty Acids, Nonesterified FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form. Fatty Acids, Free,Free Fatty Acid,Free Fatty Acids,NEFA,Acid, Free Fatty,Acids, Free Fatty,Acids, Nonesterified Fatty,Fatty Acid, Free,Nonesterified Fatty Acids
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012629 Sebum The oily substance secreted by SEBACEOUS GLANDS. It is composed of KERATIN, fat, and cellular debris. Sebums
D012636 Secretory Rate The amount of a substance secreted by cells or by a specific organ or organism over a given period of time; usually applies to those substances which are formed by glandular tissues and are released by them into biological fluids, e.g., secretory rate of corticosteroids by the adrenal cortex, secretory rate of gastric acid by the gastric mucosa. Rate, Secretory,Rates, Secretory,Secretory Rates

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