-transparent.png){kind=logo}
The authors studied the activity of natural killers in young and old mice and effects on this activity of interferon and its inducer (synthetic polynucleotide poly-I:C). The activity of natural killers as indicated by the 51Cr-release microtest and the content of the cells that recognize and lyse the target cells, determined in isolated conjugates in agarose were appreciably lower in old mice than in young ones. Administration of poly-I:C or interferon to the animals (or interferon treatment of splenocytes in vitro) led to an increase in the activity of natural killers in young mice, with no significant effect on old animals' cells.
Related Publications
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
October 1990,
Biulleten' eksperimental'noi biologii i meditsiny,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
January 2015,
Tsitologiia,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
April 1979,
Cellular immunology,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
January 1980,
Duodecim; laaketieteellinen aikakauskirja,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
January 1984,
Critical reviews in immunology,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
January 1983,
Nihon geka hokan. Archiv fur japanische Chirurgie,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
January 1987,
Natural immunity and cell growth regulation,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
January 1981,
Texas reports on biology and medicine,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
August 1982,
International journal of cancer,
L V Van'ko, and
N N Bakuradze, and
G T Sukhikh
March 1983,
Biochemical and biophysical research communications,
