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Chronic experiments were made on intact rabbits and rabbits with destroyed paraventricular and ventromedial nuclei of the hypothalamus to explore the hydrocortisone-induced inhibition of the stressor response of the pituitary-adrenocortical system. Intravenous injection of hydrocortisone in a dose of 100 micrograms/kg 5 minutes before immobilization stress led to inhibition of corticosteroid elevation induced by immobilization of the animals. Inhibition of the stressor reaction was maximal in intact animals, less in rabbits with destroyed ventromedial nuclei, and further less in animals with destroyed paraventricular nuclei. The paraventricular and ventromedial nuclei of the hypothalamus are necessary for inhibition of the pituitary-adrenocortical system by the feedback mechanisms.
A A Filaretov, and
L P Filaretova
January 1994,
Vestnik Rossiiskoi akademii meditsinskikh nauk,
A A Filaretov, and
L P Filaretova
September 1970,
Terapevticheskii arkhiv,
A A Filaretov, and
L P Filaretova
October 1970,
Horumon to rinsho. Clinical endocrinology,
A A Filaretov, and
L P Filaretova
January 1990,
Problemy endokrinologii,
A A Filaretov, and
L P Filaretova
May 1988,
Experimental and clinical endocrinology,
A A Filaretov, and
L P Filaretova
November 1970,
Biulleten' eksperimental'noi biologii i meditsiny,
A A Filaretov, and
L P Filaretova
January 1969,
Arkhiv patologii,
A A Filaretov, and
L P Filaretova
January 1988,
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
A A Filaretov, and
L P Filaretova
January 1970,
Uspekhi sovremennoi biologii,
A A Filaretov, and
L P Filaretova
January 1967,
Acta neurovegetativa,
