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We examined the nasal responsiveness to topical methacholine application in allergic rhinitis and non-allergic chronic rhinitis patients, and in control subjects. Methacholine responsiveness was significantly higher in allergic rhinitis patients than in non-allergic patients and control subjects. In perennial rhinitis, methacholine responsiveness correlated with the severity of daily nasal symptoms and those provoked by specific allergen challenge tests. Among nasal symptoms, hyper-rhinorrhoea was found to be closely related to methacholine responsiveness. As a result of these findings, the possibility of cholinergic hyper-reactivity in allergic rhinitis patients is discussed.
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
November 1987,
Clinical allergy,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
April 1991,
Clinical otolaryngology and allied sciences,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
June 1994,
Annals of allergy,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
February 2009,
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
January 2002,
Respiration; international review of thoracic diseases,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
January 1998,
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
August 2013,
European annals of allergy and clinical immunology,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
February 1995,
The Journal of allergy and clinical immunology,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
January 1984,
The American review of respiratory disease,
K Asakura, and
K Enomoto, and
H Ara, and
E Azuma, and
A Kataura
April 1988,
The European respiratory journal,
