The effects of interruption on squirrel monkey temporary threshold shift to a 96-hour noise exposure. 1984

D W Nielsen, and L Franseen, and D Fowler

6 squirrel monkeys (Saimiri scuireus ) were exposed to an octave band of noise with a center frequency of 500 Hz under both continuous and interrupted conditions. Continuous exposures lasted for 4, 8, 16, 24, 48, 72 and 96 h, with complete recovery of hearing before the next exposure. The interrupted exposure was 96 h, long with 5-min interruptions so that temporary threshold shift (TTS) could be measured at 2, 4, 8, 12, 16, 24, 36, 48, 60, 72 and 84 h of exposure. There were no differences in TTS from 8 to 96 h of exposure between the two conditions. However, at 4 h of exposure, the interrupted exposure showed significantly less TTS (p less than 0.05) than the continuous exposure. The only difference between the exposures was a 5-min interruption at 2 h of exposure during the interrupted exposure. Thus, the interrupted-exposure method is valid for making generalizations about continuous exposures of 8 h or longer. The results also confirmed our previous finding that there was no asymptotic threshold shift for the squirrel monkey although we extended the exposure time to 96 h in this experiment. The similarity of human and squirrel monkey TTS growth functions is consistent with our earlier results and supports the suitability of the squirrel monkey as an animal model for noise-induced hearing loss in humans.

UI MeSH Term Description Entries
D008297 Male Males
D009622 Noise Any sound which is unwanted or interferes with HEARING other sounds. Noise Pollution,Noises,Pollution, Noise
D005260 Female Females
D006317 Hearing Loss, Noise-Induced Hearing loss due to exposure to explosive loud noise or chronic exposure to sound level greater than 85 dB. The hearing loss is often in the frequency range 4000-6000 hertz. Acoustic Trauma,Hearing Loss, Noise Induced,Noise-Induced Hearing Loss
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001305 Auditory Fatigue Loss of sensitivity to sounds as a result of auditory stimulation, manifesting as a temporary shift in auditory threshold. The temporary threshold shift, TTS, is expressed in decibels. Fatigue, Auditory,Temporary Threshold Shift, Auditory,Auditory Fatigues,Fatigues, Auditory
D012453 Saimiri A genus of the family CEBIDAE consisting of four species: S. boliviensis, S. orstedii (red-backed squirrel monkey), S. sciureus (common squirrel monkey), and S. ustus. They inhabit tropical rain forests in Central and South America. S. sciureus is used extensively in research studies. Monkey, Squirrel,Squirrel Monkey,Monkeys, Squirrel,Saimirus,Squirrel Monkeys

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