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Analysis of variance and Westlake's test of bioavailability data using a programmable minicalculator. 1984

A Gouyette

A program for the HP-41 CV calculator with adapted printer is described for the analysis of variance of bioavailability data based upon the areas under the curve measured during a two-way cross-over pharmacokinetic study of two different drug formulations. The program can also perform the test of Westlake to compute the 95% confidence interval and determine if both formulations are bioequivalent.

UI MeSH Term Description Entries
D003023 Cloxacillin A semi-synthetic antibiotic that is a chlorinated derivative of OXACILLIN. Chloroxacillin,Sodium Cloxacillin,Cloxacillin Sodium,Syntarpen,Tegopen,Cloxacillin, Sodium,Sodium, Cloxacillin
D003201 Computers Programmable electronic devices designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations. Calculators, Programmable,Computer Hardware,Computers, Digital,Hardware, Computer,Calculator, Programmable,Computer,Computer, Digital,Digital Computer,Digital Computers,Programmable Calculator,Programmable Calculators
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000704 Analysis of Variance A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses
D001682 Biological Availability The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action. Availability Equivalency,Bioavailability,Physiologic Availability,Availability, Biologic,Availability, Biological,Availability, Physiologic,Biologic Availability,Availabilities, Biologic,Availabilities, Biological,Availabilities, Physiologic,Availability Equivalencies,Bioavailabilities,Biologic Availabilities,Biological Availabilities,Equivalencies, Availability,Equivalency, Availability,Physiologic Availabilities

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