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Thirty-three children were followed up. There were 14 girls and 7 boys with constitutional-exogenous obesity and 12 normal children. To study proteolytic function of the pancreas, the activity of trypsin was determined by the Erlanger method modified by V.A. Shaternikov and that of its inhibitor in the blood serum by the Haverback et al. method modified by V.A. Shaternikov . Activation of trypsin and its inhibitor, depending on the degree of obesity was discovered. Activation of trypsin inhibitor points to the preservation of the compensatory possibilities of the pancreas in children with constitutional-exogenous obesity. Therefore, it is desirable that a complex of different measures should include wise dietetics promoting the normalization of disturbed processes in pathology under consideration.
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