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Bone biopsy specimens from the iliac crest were obtained during surgical operations from 45 patients with rheumatoid arthritis (RA) and 41 with osteoarthritis (OA). Control material was obtained from 20 cases of sudden death due to cardiovascular disease. By both conventional histology and image analysis techniques about a quarter of all patients showed some osteoporosis. This was equally common among the OA and RA patients. It was more common among those with transparent skin and those taking corticosteroids. The only case showing mild osteomalacia suffered from OA. No gross differences were apparent between the groups in relation to plasma biochemical studies, diet, or exposure to sunlight. These results are in striking contrast to the high incidence of osteomalacia in RA reported from the west of England; moreover they do not confirm reports of hypercalcaemia among rheumatoid subjects. We conclude that the differences regarding osteomalacia are due to selection of cases. We find no evidence that osteomalacia is specifically associated with RA.
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
April 1985,
Annals of the rheumatic diseases,
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
November 1984,
British journal of rheumatology,
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
November 2007,
MMW Fortschritte der Medizin,
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
January 1986,
Zeitschrift fur Rheumatologie,
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
March 1988,
Clinical science (London, England : 1979),
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
January 2004,
Internal medicine journal,
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
January 2016,
Reumatologia,
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
January 1955,
GP,
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
April 1948,
The Medical journal of Australia,
K C Ng, and
P A Revell, and
M Beer, and
B J Boucher, and
R D Cohen, and
H L Currey
January 2018,
Clinical calcium,
