The hydrogenation of some cis- and trans-octadecenoic acids to stearic acid by a rumen Fusocillus sp. 1984

P Kemp, and D J Lander, and F D Gunstone

The hydrogenation of a range of double-bond positional and configurational octadecenoic acid isomers (cis (delta 2 and delta 4 to delta 13) and trans (delta 2 and delta 5 to delta 13] to stearic acid by a rumen Fusocillus sp. were examined. The cis and trans delta 5 to delta 13 isomers were all hydrogenated to some extent by late-log-phase cultures added to suspensions of individual isomers and incubated for a further 3 h. Of the cis-isomers, delta 5 to delta 11 (79-73% conversion to stearic acid) were the preferred substrates. delta 12-cis- (30%) and delta 13-cis-isomers (5%) were poorly hydrogenated. Of the trans-isomers, delta 8, delta 9 and delta 10 were 45% converted to stearic acid, the other isomers were poorly hydrogenated. These results are in agreement with less extensive studies using sheep rumen micro-organisms. When cultures were grown from small inocula in media containing individual isomers more extensive hydrogenation was found than with late-log-phase cultures. At 24 h, cis delta 2, delta 4 and delta 5 gave the highest conversions to stearic acid (90%) followed by the cis delta 6 to delta 12 and trans delta 8 to delta 10 isomers (approximately 75%), although at 6 and 12 h delta 9-trans gave higher yields of stearic acid than delta 9-cis, probably because the growth of the cis cultures showed a longer log-phase.

UI MeSH Term Description Entries
D008297 Male Males
D009829 Oleic Acids A group of fatty acids that contain 18 carbon atoms and a double bond at the omega 9 carbon. Octadecenoic Acids,Acids, Octadecenoic,Acids, Oleic
D005673 Fusobacterium A genus of gram-negative, anaerobic, rod-shaped bacteria found in cavities of humans and other animals. No endospores are formed. Some species are pathogenic and occur in various purulent or gangrenous infections. Sphaerophorus
D006865 Hydrogenation Addition of hydrogen to a compound, especially to an unsaturated fat or fatty acid. (From Stedman, 26th ed) Hydrogenations
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012417 Rumen The first stomach of ruminants. It lies on the left side of the body, occupying the whole of the left side of the abdomen and even stretching across the median plane of the body to the right side. It is capacious, divided into an upper and a lower sac, each of which has a blind sac at its posterior extremity. The rumen is lined by mucous membrane containing no digestive glands, but mucus-secreting glands are present in large numbers. Coarse, partially chewed food is stored and churned in the rumen until the animal finds circumstances convenient for rumination. When this occurs, little balls of food are regurgitated through the esophagus into the mouth, and are subjected to a second more thorough mastication, swallowed, and passed on into other parts of the compound stomach. (From Black's Veterinary Dictionary, 17th ed) Rumens
D012756 Sheep Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS. Ovis,Sheep, Dall,Dall Sheep,Ovis dalli
D013229 Stearic Acids A group of compounds that are derivatives of octadecanoic acid which is one of the most abundant fatty acids found in animal lipids. (Stedman, 25th ed) Dihydrooleic Acids,Octadecanoic Acids,Tetrahydrolinoleic Acids,Acids, Dihydrooleic,Acids, Octadecanoic,Acids, Stearic,Acids, Tetrahydrolinoleic
D013237 Stereoisomerism The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed) Molecular Stereochemistry,Stereoisomers,Stereochemistry, Molecular,Stereoisomer

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