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Four new human non-small cell lung cancer cell lines have been established in vitro. These cell lines have been characterized by (a) growth of a tumor in nude mice with histopathology similar to that of the primary, (b) isoenzyme patterns phenotypically human and distinct from each other, (c) distinguishing karyotypic findings, (d) growth rate determinations, and (e) presence of epidermal growth factor receptors. Each of the cell lines will form colonies when directly seeded into a flask without soft agar. The development and availability of the four cell lines may facilitate in vitro studies of the biology of this common cancer. Their clonogenic potential may be of value in the study of sensitivity to antineoplastic agents. Their low passage level may mean that their antigens still resemble those of the primary tumor.
P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
January 2012,
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P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
June 2005,
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P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
February 1993,
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P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
October 2011,
Cancer letters,
P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
January 1994,
Anticancer research,
P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
January 2000,
Anticancer research,
P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
January 2010,
Molecular medicine reports,
P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
August 1991,
Chest,
P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
May 1995,
Japanese journal of cancer research : Gann,
P M Loh, and
G H Clamon, and
R A Robinson, and
M L White, and
B Hukku, and
N P Rossi, and
W D Peterson
January 1995,
Oncology research,
