Biomaterial Database

Circulating immune complexes and sperm antibodies following vasectomy in Austrian men. 1984

S S Witkin, and N J Alexander, and J Frick

The incidence of circulating immune complexes (CICs) following vasectomy in men and the timing of their appearance and disappearance remain unsettled. A prospective study was initiated to measure CICs and sperm antibody formation in 44 Austrian men undergoing a vasectomy. Using the Raji cell assay, the incidence of CICs was 11% (5 of 44) prior to surgery, 24% (10 of 42) at 2-3 months, 10% (1 of 10) at 4-6 months and 0% (0 of 23) at 15-26 months following surgery. The incidence of sperm antibodies, employing a sperm agglutination assay and an enzyme-linked immunosorbent assay, was 7% (3 of 44), 17% (9 of 52), 25% (3 of 12) and 27% (3 of 11), at 0, 2-6, 15-20 and 21-26 months following vasectomy, respectively. CICs and sperm antibody levels were not correlated at any time point. These results support previous studies indicating a transient increase in the incidence of CICs, detectable by the Raji cell assay, only at early times following vasectomy.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000936	Antigen-Antibody Complex	The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.	Immune Complex,Antigen-Antibody Complexes,Immune Complexes,Antigen Antibody Complex,Antigen Antibody Complexes,Complex, Antigen-Antibody,Complex, Immune,Complexes, Antigen-Antibody,Complexes, Immune
D001317	Austria	A country located in Central Europe, north of Italy and Slovenia. The capital is Vienna.
D001323	Autoantibodies	Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them.	Autoantibody
D013094	Spermatozoa	Mature male germ cells derived from SPERMATIDS. As spermatids move toward the lumen of the SEMINIFEROUS TUBULES, they undergo extensive structural changes including the loss of cytoplasm, condensation of CHROMATIN into the SPERM HEAD, formation of the ACROSOME cap, the SPERM MIDPIECE and the SPERM TAIL that provides motility.	Sperm,Spermatozoon,X-Bearing Sperm,X-Chromosome-Bearing Sperm,Y-Bearing Sperm,Y-Chromosome-Bearing Sperm,Sperm, X-Bearing,Sperm, X-Chromosome-Bearing,Sperm, Y-Bearing,Sperm, Y-Chromosome-Bearing,Sperms, X-Bearing,Sperms, X-Chromosome-Bearing,Sperms, Y-Bearing,Sperms, Y-Chromosome-Bearing,X Bearing Sperm,X Chromosome Bearing Sperm,X-Bearing Sperms,X-Chromosome-Bearing Sperms,Y Bearing Sperm,Y Chromosome Bearing Sperm,Y-Bearing Sperms,Y-Chromosome-Bearing Sperms
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D014659	Vasectomy	Surgical removal of the ductus deferens, or a portion of it. It is done in association with prostatectomy, or to induce infertility. (Dorland, 28th ed)	Intravasal Thread,Vas Ligation,Vas Occlusion,Vas Occlusion, Nonchemical,Vasectomy Seekers,Vasectomy Seekers, Refused,Intravasal Threads,Ligation, Vas,Ligations, Vas,Nonchemical Vas Occlusion,Nonchemical Vas Occlusions,Occlusion, Nonchemical Vas,Occlusion, Vas,Occlusions, Nonchemical Vas,Occlusions, Vas,Refused Vasectomy Seeker,Refused Vasectomy Seekers,Seeker, Refused Vasectomy,Seeker, Vasectomy,Seekers, Refused Vasectomy,Seekers, Vasectomy,Thread, Intravasal,Threads, Intravasal,Vas Ligations,Vas Occlusions,Vas Occlusions, Nonchemical,Vasectomies,Vasectomy Seeker,Vasectomy Seeker, Refused