Argon laser iridotomy and surgical iridectomy in treatment of primary angle-closure glaucoma. 1984

F J Go, and Y Akiba, and T Yamamoto, and Y Kitazawa

In an attempt to compare surgical peripheral iridectomy and laser iridotomy with regards to the long-term control of the intraocular pressure (IOP), analyses were carried out of the clinical records of 195 eyes of 149 primary angle-closure glaucoma patients who had undergone either peripheral iridectomy or laser iridotomy and were followed up for at least one year. One hundred and ten eyes underwent peripheral iridectomy and 85 eyes had laser iridotomy. The postoperative IOP not exceeding 20 mmHg was taken as the criterion for success. The iridectomized eyes showed no significant difference from those treated with laser iridotomy in 13 clinical factors, including age at treatment, sex, type of angle-closure glaucoma, preoperative mean IOP with medication, visual field, extent of peripheral anterior synechiae (PAS) and horizontal cup/disk (C/D) ratio. The rate of successful IOP control was obtained in 76.4% of the eyes in the peripheral iridectomy group and in 75.3% of the eyes in the laser iridotomy group. It appears that laser iridotomy is just as effective as surgical iridectomy in normalizing IOP. Discriminant analysis was done to derive a discriminant function consisting of a set of factors that will prognosticate the response of primary angle-closure glaucoma either to surgical iridectomy or to laser iridotomy. Four factors were demonstrated to be significant prognosticators. They were preoperative mean IOP with medication, visual field change, C/D ratio and PAS-index, in order of statistical significance. The discriminant function yielded the discriminant efficacy of 71.2% in overall cases.

UI MeSH Term Description Entries
D007429 Intraocular Pressure The pressure of the fluids in the eye. Ocular Tension,Intraocular Pressures,Ocular Tensions,Pressure, Intraocular,Pressures, Intraocular,Tension, Ocular,Tensions, Ocular
D007498 Iris The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D005901 Glaucoma An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed) Glaucomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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