[Effect of somatostatin on the endogenous release of secretin and pancreatic polypeptide in the dog]. 1978

L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder

In dogs with chronic duodenal and gastric fistula the effect of somatostatin (SST) on the endogenous release of secretin and pancretic polypeptide (PP) was investigated. The release of secretin following intraduodenal acid administration was significantly reduced by SST. While PP increased significantly after a test meal, its release was completely suppressed by SST.

UI MeSH Term Description Entries
D010179 Pancreas A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
D010187 Pancreatic Hormones Peptide hormones secreted into the blood by cells in the ISLETS OF LANGERHANS of the pancreas. The alpha cells secrete glucagon; the beta cells secrete insulin; the delta cells secrete somatostatin; and the PP cells secrete pancreatic polypeptide. Hormones, Pancreatic
D010455 Peptides Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS. Peptide,Polypeptide,Polypeptides
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012633 Secretin A peptide hormone of about 27 amino acids from the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level. (USAN and the USP Dictionary of Drug Names, 1994, p597) Secrepan,Secretin Citrate, Pig,Secretin Maleate, Pig,Secretin Pentacetate, Pig,Secretin Sulfate, Pig,Secretin, Pig,Secretin-KABI,Pig Secretin,Pig Secretin Citrate,Pig Secretin Maleate,Pig Secretin Pentacetate,Pig Secretin Sulfate,Secretin KABI,SecretinKABI
D013004 Somatostatin A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal. Cyclic Somatostatin,Somatostatin-14,Somatotropin Release-Inhibiting Hormone,SRIH-14,Somatofalk,Somatostatin, Cyclic,Somatotropin Release-Inhibiting Factor,Stilamin,Somatostatin 14,Somatotropin Release Inhibiting Factor,Somatotropin Release Inhibiting Hormone

Related Publications

L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
May 1986, Diabetes,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
January 1978, Advances in experimental medicine and biology,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
August 1982, Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
July 1987, Endocrinology,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
April 1986, Diabetologia,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
April 1980, Diabetes,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
January 1979, Surgical forum,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
May 2001, American journal of physiology. Gastrointestinal and liver physiology,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
April 1980, Endocrinologia japonica,
L Kayasseh, and K Gyr, and H W Haecki, and J Girard, and W W Rittmann, and G A Stalder
June 1983, Horumon to rinsho. Clinical endocrinology,
Copied contents to your clipboard!