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We treated 30 diabetic women (31 pregnancies) during the peripartum period with a continuous insulin infusion. A mean infusion rate of 1.0 micron/h maintained the mean plasma glucose concentration below 100 mg/dl in 84% of the patients; the plasma glucose concentration was below 100 mg/dl within an hour of delivery in 71% of the women. Mild hypoglycemia developed during the infusion in three women and after delivery in another patient. Only two infants of the diabetic mothers developed transient and asymptomatic hypoglycemia. We conclude that continuous insulin infusion is a practical, safe, and effective method for treating diabetic mothers during the peripartum period and suggest that this technique may decrease the frequency and severity of neonatal hypoglycemia.
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
December 1977,
Minnesota medicine,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
January 1976,
The Medical journal of Australia,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
January 1988,
Acta obstetricia et gynecologica Scandinavica,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
April 2009,
International journal of obstetric anesthesia,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
March 1973,
JAMA,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
March 1981,
Diabetologia,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
July 1988,
The Journal of laboratory and clinical medicine,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
January 1978,
Problemy endokrinologii,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
April 1988,
Diabetes research and clinical practice,
R H Caplan, and
A S Pagliara, and
E A Beguin, and
C A Smiley, and
M Bina-Frymark, and
K A Goettl, and
J M Hartigan, and
J C Tankersley, and
T M Peck
January 1996,
Journal of diabetes and its complications,
