Therapeutic plasma exchange in the immune hemolytic anemias and immunologic thrombocytopenic purpura. 1982

B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel

Thus, plasma exchange appears to have a potential but limited role in the care of antibody mediated injury of red cells or platelets. Its clearest indication appears to be in those uncommon instances of warm antibody mediated hemolysis with a highly fulminant course where the classical therapeutic measures do not have adequate time for effect. Similarly, such therapy appears to have significant potential in cases of acute immunologic thrombocytopenic purpura where some clinical contraindication to steroids, immunosuppressive agents or splenectomy exists. Acute ITP of pregnancy may provide another important setting for such a therapeutic approach. Finally, plasma exchange has been shown to provide temporary clinical stability in cases of chronic cold agglutinin disease.

UI MeSH Term Description Entries
D007075 Immunoglobulin M A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin. Gamma Globulin, 19S,IgM,IgM Antibody,IgM1,IgM2,19S Gamma Globulin,Antibody, IgM
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010951 Plasma Exchange Removal of plasma and replacement with various fluids, e.g., fresh frozen plasma, plasma protein fractions (PPF), albumin preparations, dextran solutions, saline. Used in treatment of autoimmune diseases, immune complex diseases, diseases of excess plasma factors, and other conditions. Exchange, Plasma,Exchanges, Plasma,Plasma Exchanges
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011696 Purpura, Thrombocytopenic Any form of purpura in which the PLATELET COUNT is decreased. Many forms are thought to be caused by immunological mechanisms. Purpura, Thrombopenic,Purpuras, Thrombocytopenic,Purpuras, Thrombopenic,Thrombocytopenic Purpura,Thrombocytopenic Purpuras,Thrombopenic Purpura,Thrombopenic Purpuras
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D002908 Chronic Disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2). Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D005078 Exchange Transfusion, Whole Blood Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.
D005260 Female Females

Related Publications

B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
June 2024, Blood,
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
November 2019, Presse medicale (Paris, France : 1983),
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
October 2021, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis,
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
January 2012, Kathmandu University medical journal (KUMJ),
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
September 2022, Cureus,
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
January 1991, Journal of clinical apheresis,
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
August 2020, Transfusion,
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
January 2015, Hematology. American Society of Hematology. Education Program,
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
January 1992, Nihon rinsho. Japanese journal of clinical medicine,
B D Brooks, and E A Steane, and R G Sheehan, and E P Frenkel
May 1978, Polskie Archiwum Medycyny Wewnetrznej,
Copied contents to your clipboard!