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Pregnant rats received 100 rads of X-irradiation on day 17 of gestation. Control pregnant rats were sham-irradiated on the same gestation day. The male offspring were reared under environmentally enriched, standard colony, and impoverished conditions for 30 days after weaning. Then the Hebb-Williams maze test was carried out. All the prenatally X-irradiated rats were microcephalic: their mean cerebral wet weight was 15.5% less than controls. The effect of X-irradiation was not significant in error scores and running times, whereas the effect of environment was significant in these items; initial and total error scores and running times were decreased in enriched groups compared to impoverished groups in controls as well as in X-irradiated animals.
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June 1991,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
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Behavioural brain research,
M L Seo, and
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September 1966,
Experimental neurology,
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June 1978,
Psychopharmacology,
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October 1971,
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M L Seo, and
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June 1968,
Psychological reports,
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Neurobiology of learning and memory,
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Physiology & behavior,
M L Seo, and
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Experimental neurology,
