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The hypoglycemic potencies of human insulin (recombinant DNA) and bovine NPH insulin were compared in insulin-dependent diabetic subjects. The same dosages of the two preparations were alternately injected, for two successive 5-day periods, on a twice-a-day schedule. Blood glucose profiles were monitored by finger pricking 6 times/day. Slight but significant differences in glucose time appeared, suggesting that human NPH insulin acts faster than bovine NPH, and for a shorter time.
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