-transparent.png){kind=logo}
The effect of arginine infusion on blood glucose and plasma levels of insulin, C-peptide and glucagon has been studied in leukemic children before and after treatment with L-asparaginase (10,000 U/m2/day for 10 days). Therapy induced a significant reduction in basal and peak blood glucose, insulin and C-peptide levels, while glucagon was unmodified. The conserved C-peptide-insulin molar ratio suggests the interference of L-asparaginase with proinsulin synthesis. In conclusion our results prove a decreased insulin reserve with a preserved, although reduced, beta-cell function.
Related Publications
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
June 1983,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
January 1994,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
October 2009,
Journal of pediatric hematology/oncology,
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
August 1983,
The Journal of the American Osteopathic Association,
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
September 1981,
The Journal of physiology,
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
November 1970,
Gan no rinsho. Japan journal of cancer clinics,
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
January 1989,
Developmental pharmacology and therapeutics,
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
January 1986,
Pancreas,
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
January 1971,
Annales de l'Institut Pasteur de Lille,
F Meschi, and
B di Natale, and
G F Rondanini, and
C Uderzo, and
M Jankovic, and
G Masera, and
G Chiumello
January 1967,
Science (New York, N.Y.),
