According to the examinations of the authors the administration of Canesten vaginal tablets for treatment of vulvovaginitis caused by blastospores resulted in 81% of the cases in a lasting healing, in cases with an affected anamnesis in 75%. With additional treatments of Canesten solution and cream administration the efficiency was further increased and thus results of 90% or 76%, respectively could be achieved. With sanitation of auto- and heteroinfectious foci the recurrences of fungal infections could be avoided. There had been no teratogeneous effects in the newborns following Canesten treatment in pregnants. In course of Clotrimazol administration general characteristic side effects were not observed, a slight and quickly passing inflammation occured in few cases.