Optic disc and visual field changes in primary open angle glaucoma. 1981

I Goldberg
Department of Ophthalmology, Prince of Wales Hospital & University of New South Wales, Randwick.

Rapid and accurate detection of glaucomatous damage at its onset or on its progression is desirable for optimum patient management. Tonometry alone is insufficient in ensuring adequacy of therapy; also required are stereoscopic optic disc review and quantitative perimetry. Signs of early optic nerve head damage from primary open angle glaucoma (POAG) include nerve fibre layer haemorrhage, a generalised increase in optic cup size and a localised increase in optic cup size. The latter two are absolute indications for initiation or acceleration of ocular hypotensive therapy. Accurate perimetric plotting of the normal blind spot, careful examination for a nasal step, and a thorough search of the paracentral area of the visual field are recommended for detection of the earliest visual field changes in POAG. Paracentral scotomata, nasal steps and repeated asymmetric concentric contraction of the isopters are three early, specific signs of nerve fibre bundle damage.

UI MeSH Term Description Entries
D009412 Nerve Fibers Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM. Cerebellar Mossy Fibers,Mossy Fibers, Cerebellar,Cerebellar Mossy Fiber,Mossy Fiber, Cerebellar,Nerve Fiber
D009898 Optic Disk The portion of the optic nerve seen in the fundus with the ophthalmoscope. It is formed by the meeting of all the retinal ganglion cell axons as they enter the optic nerve. Blind Spot,Optic Disc,Optic Nerve Head,Optic Papilla,Blind Spots,Disc, Optic,Disk, Optic,Head, Optic Nerve,Nerve Head, Optic,Optic Discs,Optic Disks,Optic Nerve Heads,Optic Papillas,Papilla, Optic,Papillas, Optic,Spot, Blind
D005128 Eye Diseases Diseases affecting the eye. Eye Disorders,Eye Disease,Eye Disorder
D005902 Glaucoma, Open-Angle Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris. Glaucoma Simplex,Glaucoma, Pigmentary,Glaucoma, Simple,Open-Angle Glaucoma,Chronic Primary Open Angle Glaucoma,Glaucoma, Compensated,Glaucoma, Compensative,Glaucoma, Open Angle,Glaucoma, Primary Open Angle,Glaucoma, Secondary Open Angle,Primary Open Angle Glaucoma,Secondary Open Angle Glaucoma,Compensated Glaucoma,Compensative Glaucoma,Open Angle Glaucoma,Open Angle Glaucomas,Open-Angle Glaucomas,Pigmentary Glaucoma,Simple Glaucoma,Simplex, Glaucoma,Simplices, Glaucoma
D006470 Hemorrhage Bleeding or escape of blood from a vessel. Bleeding,Hemorrhages
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012607 Scotoma A localized defect in the visual field bordered by an area of normal vision. This occurs with a variety of EYE DISEASES (e.g., RETINAL DISEASES and GLAUCOMA); OPTIC NERVE DISEASES, and other conditions. Scotoma, Arcuate,Scotoma, Bjerrum,Scotoma, Central,Scotoma, Centrocecal,Scotoma, Altitudinal,Scotoma, Paracecal,Scotoma, Paracentral,Scotoma, Peripheral,Scotoma, Ring,Scotoma, Scintillating,Scotoma, Sector,Altitudinal Scotoma,Altitudinal Scotomas,Arcuate Scotoma,Arcuate Scotomas,Bjerrum Scotoma,Bjerrum Scotomas,Central Scotoma,Central Scotomas,Centrocecal Scotoma,Centrocecal Scotomas,Paracecal Scotoma,Paracecal Scotomas,Paracentral Scotoma,Paracentral Scotomas,Peripheral Scotoma,Peripheral Scotomas,Ring Scotoma,Ring Scotomas,Scintillating Scotoma,Scintillating Scotomas,Scotomas,Scotomas, Altitudinal,Scotomas, Arcuate,Scotomas, Bjerrum,Scotomas, Central,Scotomas, Centrocecal,Scotomas, Paracecal,Scotomas, Paracentral,Scotomas, Peripheral,Scotomas, Ring,Scotomas, Scintillating,Scotomas, Sector,Sector Scotoma,Sector Scotomas
D014794 Visual Fields The total area or space visible in a person's peripheral vision with the eye looking straightforward. Field, Visual,Fields, Visual,Visual Field

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