Adrenal medullary disease in multiple endocrine neoplasia type II. 1980

K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza

The diagnosis of multiple endocrine neoplasia type II (MEN-II) was made in 18 patients from 1966 through 1978 at the University of Michigan Medical Center. Eight patients had adrenal medullary disease. Seven had bilateral adrenal pheocyromocytomas (two with concomitant medullary hyperplasia) and one had a unilateral pheochromocytoma with contralateral medullary hyperplasia. No malignant or extraadrenal pheochromocytomas were found. Pheochromocytomas in patients with MEN-II are multiple and involve both adrenal glands. Adrenal venography is advocated as the primary diagnostic tool for localization of adrenal medullary disease in MEN-II patients.

UI MeSH Term Description Entries
D006965 Hyperplasia An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. Hyperplasias
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009378 Neoplasms, Multiple Primary Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites. Neoplasms, Synchronous,Neoplasms, Synchronous Multiple Primary,Multiple Primary Neoplasms,Multiple Primary Neoplasms, Synchronous,Synchronous Multiple Primary Neoplasms,Synchronous Neoplasms,Multiple Primary Neoplasm,Neoplasm, Multiple Primary,Neoplasm, Synchronous,Primary Neoplasm, Multiple,Primary Neoplasms, Multiple,Synchronous Neoplasm
D010673 Pheochromocytoma A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298) Pheochromocytoma, Extra-Adrenal,Extra-Adrenal Pheochromocytoma,Extra-Adrenal Pheochromocytomas,Pheochromocytoma, Extra Adrenal,Pheochromocytomas,Pheochromocytomas, Extra-Adrenal
D010690 Phlebography Radiographic visualization or recording of a vein after the injection of contrast medium. Venography,Phlebographies,Venographies
D002277 Carcinoma A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for "cancer." Carcinoma, Anaplastic,Carcinoma, Spindle-Cell,Carcinoma, Undifferentiated,Carcinomatosis,Epithelial Neoplasms, Malignant,Epithelioma,Epithelial Tumors, Malignant,Malignant Epithelial Neoplasms,Neoplasms, Malignant Epithelial,Anaplastic Carcinoma,Anaplastic Carcinomas,Carcinoma, Spindle Cell,Carcinomas,Carcinomatoses,Epithelial Neoplasm, Malignant,Epithelial Tumor, Malignant,Epitheliomas,Malignant Epithelial Neoplasm,Malignant Epithelial Tumor,Malignant Epithelial Tumors,Neoplasm, Malignant Epithelial,Spindle-Cell Carcinoma,Spindle-Cell Carcinomas,Tumor, Malignant Epithelial,Undifferentiated Carcinoma,Undifferentiated Carcinomas
D003951 Diagnostic Errors Incorrect or incomplete diagnoses following clinical or technical diagnostic procedures. Diagnostic Blind Spots,Errors, Diagnostic,Misdiagnosis,Blind Spot, Diagnostic,Blind Spots, Diagnostic,Diagnostic Blind Spot,Diagnostic Error,Error, Diagnostic,Misdiagnoses
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
June 1977, American journal of clinical pathology,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
March 1994, Endocrinology and metabolism clinics of North America,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
August 1976, American journal of clinical pathology,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
January 1990, Revista do Hospital das Clinicas,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
January 1990, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
January 1976, Annual review of medicine,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
May 1978, Nihon rinsho. Japanese journal of clinical medicine,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
July 1970, Surgery,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
January 1981, Ergebnisse der inneren Medizin und Kinderheilkunde,
K J Cho, and D T Freier, and T L McCormick, and R H Nishiyama, and M E Forrest, and A Kaufman, and G S Borlaza
August 2002, World journal of surgery,
Copied contents to your clipboard!