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Simultaneous left ventricular echograms and high-gain pressure recordings were made during 30 s of regional myocardial ischemia induced by snare occlusions of the proximal left anterior descending (LAD) or left circumflex (LCx) coronary arteries in open-chest dogs. Left ventricular diastolic diameter (d) and pressure (p) were measured during slow filling. A normalized (for diameter D) distensibility estimate (DE = delta d/delta p/D) was calculated, as were slow filling slopes (SFSs) of the septum and posterior wall. After occlusion, significant (p less than 0.05) decreases of DE and anterior and posterior left-ventricular-wall mid-diastolic normalized slow-filling slopes (ASFS/D and PSFS/D) were observed. Correlations were noted between percentage decreases of DE and ASFS/D (r = 0.69, p less than 0.0001) and PSFS/D (r = 0.62, p less than 0.0001). No significant differences between decreases of DE and SFS were noted between ischemic and non-ischemic regions. Transient regional myocardial ischemia was associated with a generalized alteration in left ventricular filling patterns in mid-diastole.
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
January 1976,
Surgical forum,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
October 1989,
Masui. The Japanese journal of anesthesiology,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
March 1970,
Circulation research,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
March 1981,
The American journal of physiology,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
February 1990,
Circulation,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
August 1990,
British heart journal,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
April 1997,
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
October 1994,
Cardiovascular drugs and therapy,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
January 1997,
Anesthesia and analgesia,
D A Conetta, and
L G Christie, and
R L Feldman, and
W W Nichols, and
C J Pepine, and
C R Conti
August 1993,
Circulation,
