BIOMAT Database Logo BIOMAT Database Logo

Activation and characterization of inactive big renin in plasma of patients with diabetic nephropathy and unusual active renin. 1980

W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis

UI MeSH Term Description Entries
D008970 Molecular Weight The sum of the weight of all the atoms in a molecule. Molecular Weights,Weight, Molecular,Weights, Molecular
D010434 Pepsin A Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice. Pepsin,Pepsin 1,Pepsin 3
D012083 Renin A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19. Angiotensin-Forming Enzyme,Angiotensinogenase,Big Renin,Cryorenin,Inactive Renin,Pre-Prorenin,Preprorenin,Prorenin,Angiotensin Forming Enzyme,Pre Prorenin,Renin, Big,Renin, Inactive
D002850 Chromatography, Gel Chromatography on non-ionic gels without regard to the mechanism of solute discrimination. Chromatography, Exclusion,Chromatography, Gel Permeation,Chromatography, Molecular Sieve,Gel Filtration,Gel Filtration Chromatography,Chromatography, Size Exclusion,Exclusion Chromatography,Gel Chromatography,Gel Permeation Chromatography,Molecular Sieve Chromatography,Chromatography, Gel Filtration,Exclusion Chromatography, Size,Filtration Chromatography, Gel,Filtration, Gel,Sieve Chromatography, Molecular,Size Exclusion Chromatography
D003928 Diabetic Nephropathies KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE. Diabetic Glomerulosclerosis,Glomerulosclerosis, Diabetic,Diabetic Kidney Disease,Diabetic Nephropathy,Intracapillary Glomerulosclerosis,Kimmelstiel-Wilson Disease,Kimmelstiel-Wilson Syndrome,Nodular Glomerulosclerosis,Diabetic Kidney Diseases,Glomerulosclerosis, Nodular,Kidney Disease, Diabetic,Kidney Diseases, Diabetic,Kimmelstiel Wilson Disease,Kimmelstiel Wilson Syndrome,Nephropathies, Diabetic,Nephropathy, Diabetic,Syndrome, Kimmelstiel-Wilson
D004789 Enzyme Activation Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme. Activation, Enzyme,Activations, Enzyme,Enzyme Activations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006863 Hydrogen-Ion Concentration The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D006947 Hyperkalemia Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed) Hyperpotassemia,Hyperkalemias,Hyperpotassemias
D014357 Trypsin A serine endopeptidase that is formed from TRYPSINOGEN in the pancreas. It is converted into its active form by ENTEROPEPTIDASE in the small intestine. It catalyzes hydrolysis of the carboxyl group of either arginine or lysine. EC 3.4.21.4. Tripcellim,Trypure,beta-Trypsin,beta Trypsin

Related Publications

W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
Response of plasma immunoreactive active renin, inactive renin, plasma renin activity, and aldosterone to hemodialysis in patients with diabetic nephropathy.
June 1990, Clinical nephrology,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
The inactive to active renin ratio in the kidneys and the plasma in diabetic nephropathy.
January 1983, Japanese circulation journal,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
Plasma active and inactive renin in patients with diabetes mellitus.
February 1980, Endocrinologia japonica,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
Plasma active renin, inactive renin and kallikrein in patients with disseminated intravascular coagulation.
May 1991, Journal of the Formosan Medical Association = Taiwan yi zhi,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
[Big renin (inactive renin) and renin substrate].
October 1979, Nihon rinsho. Japanese journal of clinical medicine,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
Active, inactive and total renin concentrations in plasma of hypertensive patients.
April 1985, The Tohoku journal of experimental medicine,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
Active and inactive renin in human seminal plasma.
August 1981, Archives of andrology,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
Plasma active and inactive renin concentrations in children.
January 1990, Hormone research,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
Binding of human renin to plasma proteins and comparison with plasma active and inactive renin.
February 1985, Journal of hypertension,
W A Hsueh, and E J Carlson, and J A Luetscher, and G Grislis
Plasma inactive renin in patients with hyperthyroidism.
January 1983, The Journal of clinical endocrinology and metabolism,
Copied contents to your clipboard!