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1. A breath-by-breath analysis was made of tracheal pressure records from fetal lambs in utero at 117--130 days gestation. 2. Episodes of rapid irregular breathing were accompanied by diaphragmatic e.m.g. activity and were characterized by a gradual increase in breathing rate initially and a terminal decline. Within each episode breathing was very irregular. 3. Inspiratory time increased with increasing expiratory time rapidly as the rate fell to about 80/min, and thereafter more slowly. 4. The principal effects of hypercapnia (a rise in fetal Pa, CO2 by approximately 11 mmHg) were to increase the depth of fetal breathing, by nearly twofold, and to make breathing much more regular. A change in rate was doubtful because of the skew distribution of normal breath intervals.
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
January 1997,
Pediatric research,
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
April 1983,
Respiration physiology,
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
January 1984,
Respiration physiology,
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
February 1997,
Acta obstetricia et gynecologica Scandinavica,
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
August 1994,
Journal of applied physiology (Bethesda, Md. : 1985),
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
February 1987,
Journal of applied physiology (Bethesda, Md. : 1985),
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
August 1985,
European journal of obstetrics, gynecology, and reproductive biology,
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
March 1982,
American journal of obstetrics and gynecology,
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
May 1993,
Medical & biological engineering & computing,
R L Chapman, and
G S Dawes, and
D W Rurak, and
P L Wilds
May 1985,
The Journal of physiology,
