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Commerical preparations of cryoprecipitates, factor VIII concentrates of intermediate purity, and factor VIII concentrates of high purity were studied for their factor VIII related clotting- and platelet-aggregating activities as well as their content of factor VIII antigen. The ratios of the values obtained of these three parameters were used to determine the extent of inactivation of the factor in the preparations. By means of two-dimensional immunelectrophoresis and gel chromatography on Sepharose 4B, the preparations were tested for the presence of atypical factor VIII molecules. Investigations were made to qualify and quantify some of the concomitant proteins in the factor VIII preparations.
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
January 1979,
Arzneimittel-Forschung,
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
August 1980,
Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca,
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
July 1995,
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis,
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
January 1978,
Annali dell'Istituto superiore di sanita,
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
January 1975,
Vox sanguinis,
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
June 1993,
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis,
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
June 1992,
Lancet (London, England),
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
May 1979,
Medizinische Klinik,
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
November 1977,
Klinische Padiatrie,
T Vukovich, and
E Koller, and
W Doleschel, and
W R Mayr
June 1988,
Blood,
