The new variant carbonic anhydrase in the Japanese: CAINagasaki 1(76 Arg replaced by Gln) and CAIHiroshima 2. 1980

K Goriki, and S Kawamoto, and R E Tashian

Hemolysates obtained from 4,919 residents of Hiroshima and 4,131 residents of Nagasaki for a total of 9,050 were examined for carbonic anhydrase I (CAI) using vertical starch gel electrophoresis. Eight inherited variants of carbonic anhydrase I, designated CAIHiroshima 1 (CAIHIR 1), were detected and two new fast variants of CAI were detected in one Nagasaki resident and in one Hiroshima resident. These fast variants were designated CAINagasaki 1 (CAINGS 1) and CAI Hiroshima 2 (CAIHIR 2). The isoelectric point of CAINGS 1 was 5.95 and that of CAIHIR 2 was 6.20.

UI MeSH Term Description Entries
D007527 Isoenzymes Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics. Alloenzyme,Allozyme,Isoenzyme,Isozyme,Isozymes,Alloenzymes,Allozymes
D007564 Japan A country in eastern Asia, island chain between the North Pacific Ocean and the Sea of Japan, east of the Korean Peninsula. The capital is Tokyo. Bonin Islands
D002256 Carbonic Anhydrases A family of zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide. They play an important role in the transport of CARBON DIOXIDE from the tissues to the LUNG. EC 4.2.1.1. Carbonate Dehydratase,Carbonic Anhydrase,Anhydrases, Carbonic,Dehydratase, Carbonate
D004592 Electrophoresis, Starch Gel Electrophoresis in which a starch gel (a mixture of amylose and amylopectin) is used as the diffusion medium. Starch Gel Electrophoresis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014644 Genetic Variation Genotypic differences observed among individuals in a population. Genetic Diversity,Variation, Genetic,Diversity, Genetic,Diversities, Genetic,Genetic Diversities,Genetic Variations,Variations, Genetic

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