Biomaterial Database

[Long-term treatment of bronchial asthma with disodiumcromoglycate (Intal) (author's transl)]. 1980

W Schlick

26 patients with chronic perennial bronchial asthma were treated with disodiumcromoglycate (Intal). The drug was administered by spinhaler in a daily dose of 4 capsules à 20 mg. There was significant clinical improvement within the first three months of treatment. Airway resistance showed a statistically significant decrease after three months of DSCG treatment. 15 of the 26 patients had been on long-term steroid treatment, in 9 of these 15 patients steroid therapy could be discontinued completely. It is stated that DSCG is effective also in nonallergic bronchial asthma, that there is not only significant clinical improvement, but also functional improvement after three months of DSCG, and that in some steroid dependent asthmatics reduction or complete withdrawal of steroid therapy can be achieved.

UI	MeSH Term	Description	Entries
D004205	Cromolyn Sodium	A chromone complex that acts by inhibiting the release of chemical mediators from sensitized MAST CELLS. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.	Disodium Cromoglycate,Sodium Cromoglycate,Aarane,Bicromat Spray,Cromoglicic Acid,Cromoglycate,Cromoglycic Acid,Cromolyn,FPL-670,Intal,Lomudal,Nalcrom,Nasalcrom,Opticrom,Vicrom,Acid, Cromoglicic,Acid, Cromoglycic,Cromoglycate, Disodium,Cromoglycate, Sodium,FPL 670,FPL670
D004334	Drug Administration Schedule	Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience.	Administration Schedule, Drug,Administration Schedules, Drug,Drug Administration Schedules,Schedule, Drug Administration,Schedules, Drug Administration
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000403	Airway Resistance	Physiologically, the opposition to flow of air caused by the forces of friction. As a part of pulmonary function testing, it is the ratio of driving pressure to the rate of air flow.	Airway Resistances,Resistance, Airway,Resistances, Airway
D001249	Asthma	A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).	Asthma, Bronchial,Bronchial Asthma,Asthmas