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Unusual radiographic manifestations of amebiasis have not previously been emphasized in the literature. These unusual manifestations often mimic other, more common disease entities. A recent case of urinary bladder-cervical amebiasis prompted a review of other unusual manifestations of amebiasis. Over a 25-year period, unusual cases involving the musculoskeletal, genitourinary, cardiopulmonary, and gastrointestinal systems have been encountered. Primary amebiasis of any organ may occur without clinical evidence of gastrointestinal or hepatic involvement. These unusual cases illustrate the clinical spectrum of amebiasis and will clarify aspects of this interesting disease entity.
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