Concentrated Totamin was administered by venous infusion in 32 pediatric patients, aged 2 days to 13 years. In 17 cases (group "A"), patients received Totamin by separated and isolated infusion, which was followed by serum glucose and electrolytes infusion. N intake was 0.17-0.32 g/kg/day (m = 0.23), caloric intake was 5-50 cal/kg/day (m = 25), duration of treatment was 5,17 days. In 15 cases (group "B") patients received Totamin, serum glucose and electrolytes simultaneously. N intake was 0.07-0.26 g/kg/day (m = 0.17), caloric intake was 20-72 cal/kg/day (m = 47), duration of treatment was 5 days. The N positive or equilibrate total positive balance ratio is identical in both the groups = 12/17 (70.6%) in group "A" and 10/15 (66.7%) in group "B". But in 11 patients (5 of group "A" and 6 of group "B") which received an identical N intake (0.20 g/kg/day) N balance was negative in 5 (A) and positive in 6 (B). Thus its appears that for an identical N intake, serum glucose infusion simultaneously with concentrated Totamin, is a more efficacious treatment than alternate infusion. Simultaneous infusion produces and better utilisation of Totamin and a N positive balance.