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Experimental protein-calorie malnutrition was produced in rats by giving them a low-protein diet for 6 weeks. Control animals were fed a high-protein diet. The deficient rats showed severe restriction of body weight gain, fatty liver and hypoproteinaemia. In addition the present study demonstrates that the experimentally induced protein-calorie malnutrition brings about marked pathological changes and increased catecholamine levels in the hearts of rats. Based on this demonstration, and considering the synchronism of morphological and biochemical data, we postulate that the nutritional stress to the heart raises the myocardium noradrenaline concentration and the continued exposure to high levels of catecholamines may play a role in the development of cardiac changes in protein-energy malnutrition.
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
November 1974,
The Medical clinics of North America,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
August 1968,
The American journal of clinical nutrition,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
June 1972,
Experimental and molecular pathology,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
February 1968,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
September 1971,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
August 1986,
Nutrition reviews,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
October 1983,
Journal of postgraduate medicine,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
December 1972,
The Journal of clinical endocrinology and metabolism,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
June 1968,
Archives of disease in childhood,
M A Rossi, and
O Pissaia, and
Y Cury, and
J S Oliveira
January 1976,
Lancet (London, England),
