BIOMAT Database Logo BIOMAT Database Logo

Cis-dichlorodiammineplatinum (II): A new antitumor agent. 1978

J M Rainey

UI MeSH Term Description Entries
D009369 Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D002945 Cisplatin An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle. Platinum Diamminodichloride,cis-Diamminedichloroplatinum(II),cis-Dichlorodiammineplatinum(II),Biocisplatinum,Dichlorodiammineplatinum,NSC-119875,Platidiam,Platino,Platinol,cis-Diamminedichloroplatinum,cis-Platinum,Diamminodichloride, Platinum,cis Diamminedichloroplatinum,cis Platinum
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

J M Rainey
Antitumor activity of cis-dichlorodiammineplatinum(II).
January 1979, Cancer treatment reports,
J M Rainey
The chemical and biological effects of cis-dichlorodiammineplatinum (II), an antitumor agent, on DNA.
November 1974, Proceedings of the National Academy of Sciences of the United States of America,
J M Rainey
Radiation-induced DNA damage and lethality in E. coli as modified by the antitumor agent cis-dichlorodiammineplatinum (II).
August 1977, Radiation research,
J M Rainey
Nephrotoxicity of cis-dichlorodiammineplatinum(II).
January 1979, Cancer treatment reports,
J M Rainey
[Pharmacokinetics of cis-dichlorodiammineplatinum (II)].
April 1982, Gan to kagaku ryoho. Cancer & chemotherapy,
J M Rainey
[Antitumor action of cis-dichlorodiammineplatinum(II) and the effectiveness of a combination with sarcolysine].
January 1978, Voprosy onkologii,
J M Rainey
[Nephrotoxicity mechanisms of the antitumor preparation, cis-dichlorodiammineplatinum].
January 1979, Voprosy onkologii,
J M Rainey
[Antitumor activity of cis-dichlorodiammineplatinum(II) and its effect on cell cycle progression].
April 1982, Gan to kagaku ryoho. Cancer & chemotherapy,
J M Rainey
cis-Dichlorodiammineplatinum(II) in childhood cancer.
January 1979, Cancer treatment reports,
J M Rainey
Cytostatic activity in vitro of new cis-dichlorodiammineplatinum (II) analogs.
January 1982, Archivum immunologiae et therapiae experimentalis,
Copied contents to your clipboard!