-transparent.png){kind=logo}
An anti-IgG activity has previously been reported at the cellular level in patients with psoriasis. This activity was demonstrated by the so-called 'rheumatoid' rosette test. In the present work the nature of 'rheumatoid' rosette-forming cells was studied in comparison with other EA rosette techniques. The use of purified cell populations showed that the lymphocytes participating in the 'rheumatoid' rosette phenomenon were lacking conventional T and B cell membrane markers, and were thus referred to as null cells. Such mononuclear cells bearing a receptor for the Fc part of IgG were able to act as killer cells to IgG-coated target cells. The cytotoxic activity was mainly restricted to a small proportion of lymphocytes forming 'rheumatoid' rosettes which had a high avidity for EA complexes. Such cytotoxicity could contribute to the aetiology of lesions in psoriasis.
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
January 1979,
Acta dermato-venereologica,
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
June 1981,
Clinical and experimental immunology,
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
December 1995,
Immunology,
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
February 1997,
Journal of immunology (Baltimore, Md. : 1950),
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
April 1988,
Clinical immunology and immunopathology,
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
August 1985,
Archives of dermatology,
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
July 1977,
Ryumachi. [Rheumatism],
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
November 1980,
The Journal of clinical endocrinology and metabolism,
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
April 1994,
Placenta,
J Clot, and
J J Guilhou, and
J Meynadier, and
B Paradis, and
M Andary
July 1984,
Nihon Kyobu Shikkan Gakkai zasshi,
