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Effects of injections of two doses of nicotine (o.2 and 0.4 mg/kg body wt) were tested on general activity (in a photocell chamber) and on locomotor activity (in an activity wheel) in male and female rats of two ages (40 and 90 days). Behavior was monitored under light and dark conditions at 15, 30, and 45 min post-injection over a period of 12 days. A general excitatory effect of nicotine was observed in the photocell chamber, with the high dosage greatly increasing activity for younger and female animals. In the activity wheel an initial depressant effect was observed followed by excitation at the lower dose. no evidence for tolerance or difference between light and dark test conditions was found.
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
May 1985,
Pharmacology, biochemistry, and behavior,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
March 1993,
Pharmacology, biochemistry, and behavior,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
December 1992,
Pharmacology, biochemistry, and behavior,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
November 1993,
The Journal of pharmacology and experimental therapeutics,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
January 2007,
Neurotoxicology and teratology,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
September 1978,
Journal of speech and hearing research,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
January 1969,
The Journal of pharmacy and pharmacology,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
August 2010,
Behavioral neuroscience,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
May 2007,
Toxicology,
R Bryson, and
P M Biner, and
E McNair, and
M Bergondy, and
O R Abrams
January 1990,
Chronobiology international,
