-transparent.png){kind=logo}
A genetically determined, polymorphic electrophoretic variant of thyroxin-binding alpha-globulin (TBG) is found in sera from populations of African and Oceania origin, although not in Caucasians nor Orientals. The TBG polymorphism is inherited in X-linked fashion, based on data from American blacks, and thus provides an X-chromosome marker with a relatively high gene frequency in this ethnic group (frequency of the slow allele, TBGs, is 11%). This slow variant should prove valuable in expanding the map of the X chromosome and in linkage studies. An additional family exhibiting X-linked TBG deficiency is also described.
Related Publications
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
February 1984,
Biochemical genetics,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
December 1984,
Ugeskrift for laeger,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
May 1984,
American journal of human genetics,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
January 1983,
American journal of human genetics,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
April 1989,
Clinical chemistry,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
June 1989,
Clinical chemistry,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
May 1971,
Birth defects original article series,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
January 1980,
Journal of endocrinological investigation,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
October 1990,
Clinica chimica acta; international journal of clinical chemistry,
S P Daiger, and
D P Rummel, and
L Wang, and
L L Cavalli-Sforza
March 1990,
Human genetics,
