[Influence of supplementary tyrosine or phenylalanine on bacterial growth and pigmentation of "Pseudomonas aeruginosa" (author's transl)]. 1981

S Labeyrie, and E Neuzil

Pseudomonas aeruginosa grows readily on synthetic media containing succinate (36 mM) and ammonium chloride as sole source of nitrogen (34 mM) ; addition of tyrosine or phenylalanine (2,7 mM) is followed by an increase of both the growth rate and pyocyanine production. Several molecules structurally related to tyrosine give similar results. Tyrosine partially suppresses the inhibitory effect of both cyanide and azide. The results are discussed with regard to the biosynthesis of aromatic aminoacids and of phenazine pigments.

UI MeSH Term Description Entries
D010649 Phenylalanine An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE. Endorphenyl,L-Phenylalanine,Phenylalanine, L-Isomer,L-Isomer Phenylalanine,Phenylalanine, L Isomer
D010858 Pigmentation Coloration or discoloration of a part by a pigment. Pigmentations
D011550 Pseudomonas aeruginosa A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection. Bacillus aeruginosus,Bacillus pyocyaneus,Bacterium aeruginosum,Bacterium pyocyaneum,Micrococcus pyocyaneus,Pseudomonas polycolor,Pseudomonas pyocyanea
D011710 Pyocyanine Antibiotic pigment produced by Pseudomonas aeruginosa. Pyocyanin
D003470 Culture Media Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN. Media, Culture
D003486 Cyanides Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical. Cyanide,Isocyanide,Isocyanides
D001386 Azides Organic or inorganic compounds that contain the -N3 group. Azide
D014443 Tyrosine A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin. L-Tyrosine,Tyrosine, L-isomer,para-Tyrosine,L Tyrosine,Tyrosine, L isomer,para Tyrosine

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