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Two thousand three hundred and seventy strains of Shigella dysenteriae, Sh flexneri, and Sh boydii isolated in England and Wales from 1974 to 1978 were tested for resistance to 12 antimicrobial drugs. Eighty per cent of strains were resistant to one or more drugs, with sulphonamide resistance occurring most frequently. Resistance to streptomycin, tetracycline, ampicillin, and chloramphenicol increased during the period, as did the incidence of multiple resistance. Most infections due to Sh dysenteriae, Sh flexneri, and Sh boydii are acquired abroad, and the increasing incidence of drug resistance among these organisms contrasts with the decreasing incidence of resistance among the indigenous Sh sonnei. These findings may indicate the need for better control of antibiotic use, particularly in developing countries.
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
May 1982,
British medical journal (Clinical research ed.),
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
November 2001,
Biochemical and biophysical research communications,
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
October 1991,
The Journal of antimicrobial chemotherapy,
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
November 1951,
Journal of general microbiology,
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
April 1966,
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-hygienische Bakteriologie, Virusforschung und Parasitologie. Originale,
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
December 1982,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
April 2001,
Genes & genetic systems,
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
March 2009,
FEMS microbiology letters,
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
March 1974,
Medical microbiology and immunology,
R J Gross, and
B Rowe, and
T Cheasty, and
L V Thomas
January 1974,
Medical microbiology and immunology,
