Biomaterial Database

Effects of long-term turpentine inhalation on rat brain protein metabolism. 1978

H Savolainen, and P Pfäffli

Chronic exposure of adult male rats to commercial turpentine resulted in an accumulation of the solvent in perinephric fat and brain. The body solvent content remained virtually stable during 8 weeks. Brain RNA content was below the control range initially and it increased to the control level at the 4th week of exposure. Serum non-specific cholinesterase activity was somewhat below the control range at the first and second week of exposure and it returned to the control level thereafter. The present data are in agreement with the small effects of turpentine exposure on human central nervous system in clinical follow-up studies.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009419	Nerve Tissue Proteins		Proteins, Nerve Tissue,Tissue Proteins, Nerve
D001921	Brain	The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.	Encephalon
D004326	Drinking	The consumption of liquids.	Water Consumption,Water Intake,Drinkings
D004435	Eating	The consumption of edible substances.	Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes
D004798	Enzymes	Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.	Biocatalyst,Enzyme,Biocatalysts
D000336	Aerosols	Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents.	Aerosol
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D014425	Turpentine	The concrete oleoresin obtained from PINACEAE such as longleaf pine (Pinus palustris). It contains a volatile oil, to which its properties are due, and to which form it is generally used. Turpentine is used as a solvent and an experimental irritant in biomedical research.	Turpentine, Oil,Oil Turpentine