Biomaterial Database

Heterosis for H1 histone content in aging Drosophila hybrids. 1981

A O Martinez, and R G McDaniel

Temporal changes in electrophoretically separated histones were investigated in a heterotic and a non-heterotic Drosophila melanogaster F1 hybrid and in their respective inbred parents. Histones were acid-extracted from isolated nuclei of larvae and of adult flies at selected age intervals. Five major histone fractions were identified, and distinct quantitative differences in H1 histones were found between early third instar larvae and adults. Age-related quantitative histone differences were also apparent when hybrids were compared with parents. Heterotic hybrids maintained a significantly higher proportion of H1 histone fractions with aging than did all parents or non-heterotic hybrids. Relative H1 histone quantity in non-heterotic hybrids paralleled the decline observed in parents. These data suggest a relation between the manifestation of hybrid vigor and the maintenance of chromatin structure during the aging process.

UI	MeSH Term	Description	Entries
D004331	Drosophila melanogaster	A species of fruit fly frequently used in genetics because of the large size of its chromosomes.	D. melanogaster,Drosophila melanogasters,melanogaster, Drosophila
D004591	Electrophoresis, Polyacrylamide Gel	Electrophoresis in which a polyacrylamide gel is used as the diffusion medium.	Polyacrylamide Gel Electrophoresis,SDS-PAGE,Sodium Dodecyl Sulfate-PAGE,Gel Electrophoresis, Polyacrylamide,SDS PAGE,Sodium Dodecyl Sulfate PAGE,Sodium Dodecyl Sulfate-PAGEs
D005838	Genotype	The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.	Genogroup,Genogroups,Genotypes
D006657	Histones	Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.	Histone,Histone H1,Histone H1(s),Histone H2a,Histone H2b,Histone H3,Histone H3.3,Histone H4,Histone H5,Histone H7
D006823	Hybrid Vigor	The adaptive superiority of the heterozygous GENOTYPE with respect to one or more characters in comparison with the corresponding HOMOZYGOTE.	Heterosis,Vigor, Hybrid
D006824	Hybridization, Genetic	The genetic process of crossbreeding between genetically dissimilar parents to produce a hybrid.	Crossbreeding,Hybridization, Intraspecies,Crossbreedings,Genetic Hybridization,Genetic Hybridizations,Hybridizations, Genetic,Hybridizations, Intraspecies,Intraspecies Hybridization,Intraspecies Hybridizations
D000375	Aging	The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.	Senescence,Aging, Biological,Biological Aging
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia