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Many of the reactions of cellular immunity are mediated by soluble lymphocyte-derived factors (lymphokines). One important category of lymphokine action involves effects on cell motility. These effects have been described mainly with respect to inflammatory cells. In this report, we describe the ability of a lymphocyte product to inhibit the migration of endothelial cells in a system in vitro. The responsible factor is distinct from a previously described mediator that inhibits the migration of tumor cells. The ability of lymphocytes to influence the migration properties of endothelial cells is consistent with data of others showing a relation between the immune system and processes involving neovascularization.
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
September 1978,
Journal of immunology (Baltimore, Md. : 1950),
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
May 1975,
Journal of immunology (Baltimore, Md. : 1950),
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
January 1981,
Journal of immunology (Baltimore, Md. : 1950),
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
December 1985,
Clinical rheumatology,
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
November 1989,
Immunology letters,
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
September 1984,
Cancer research,
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
May 1994,
Cancer immunology, immunotherapy : CII,
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
October 1983,
Journal of immunology (Baltimore, Md. : 1950),
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
June 1988,
European journal of clinical investigation,
M C Cohen, and
P T Picciano, and
W J Douglas, and
T Yoshida, and
D L Kreutzer, and
S Cohen
October 1980,
Experimental and molecular pathology,
