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Thirty-eight depressed patients who were treated with ECT were randomly assigned to receive lithium therapy or identical-looking placebo tablets for one year after clinical recovery in a double-blind trial. The patients who received placebo tablets spent an average of 7.8 weeks with an episode of depression (either as in-patients or day-patients) during the year. In comparison, patients who received lithium spent on average 1.7 weeks with an episode (P less than 0.02). The trial confirms the high rate of relapses after ECT and suggests that lithium considerably reduces this morbidity. It is suggested that ECT without continuation therapy is not a satisfactory treatment of depressive illness.
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P Milln, and
J Bailey, and
M Metcalfe, and
B H Burns, and
A Armond
December 2011,
The journal of ECT,
A Coppen, and
M T Abou-Saleh, and
P Milln, and
J Bailey, and
M Metcalfe, and
B H Burns, and
A Armond
December 2021,
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A Coppen, and
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A Coppen, and
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A Armond
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A Coppen, and
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September 2008,
The journal of ECT,
A Coppen, and
M T Abou-Saleh, and
P Milln, and
J Bailey, and
M Metcalfe, and
B H Burns, and
A Armond
November 2005,
Der Nervenarzt,
A Coppen, and
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P Milln, and
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B H Burns, and
A Armond
December 2021,
Asian journal of psychiatry,
A Coppen, and
M T Abou-Saleh, and
P Milln, and
J Bailey, and
M Metcalfe, and
B H Burns, and
A Armond
June 1997,
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A Coppen, and
M T Abou-Saleh, and
P Milln, and
J Bailey, and
M Metcalfe, and
B H Burns, and
A Armond
June 2015,
The journal of ECT,
