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Various therapeutic methods have been attempted for cerebral infarction, but the development of more effective methods is still awaited. We have investigations of the effect of mannitol in preventing the development of cerebral infarction and have reported it effects in clinical cases of operated cerebral aneurysms. In recent years, our attention has been drawn to the so-called red cell substitute, perfluorochemicals (FC), which has a high oxygen-carrying capacity and a small particle less than 0.1 mu. In the present studies, using infarction models in dogs which have previously developed and reported, observations are made on the recovery of brain electrical activity in sever ischemia, suppressing brain swelling following recirculation of cerebral blood flow and protection upon the hemorrhagic brain infarction, due to administration of mannitol or FC. These experimental results indicate that the combined administration of mannitol and FC is effective in protecting the brain from cerebral ischemia.
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
November 1979,
Der Anaesthesist,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
January 1977,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
January 1978,
Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
March 1981,
Annales de pediatrie,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
December 1976,
EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
November 1975,
Wiener klinische Wochenschrift,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
July 1973,
Klinische Wochenschrift,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
December 1980,
Kokyu to junkan. Respiration & circulation,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
October 1977,
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
J Suzuki, and
T Yoshimoto, and
S Tanaka, and
K Mizoi, and
S Kagawa
September 1981,
Neurologia medico-chirurgica,
