-transparent.png){kind=logo}
A patient with thrombotic thrombocytopenic purpura was treated with 8 U of fresh frozen plasma, resulting in a rapid improvement in her condition and subsequently followed by a prolonged clinical remission. The transmission and scanning electron microscopic examinations of the platelets performed before treatment demonstrated marked anomalies of the platelet morphology, namely, an increased number of abnormally elongated pseudopods with terminal knobs, a decreased number of platelet granules and excess of glycogen and marked anisocytosis. These anomalies remained unchanged when reexamined 2 months after the achievement of the clinical remission. The question whether these platelet abnormalities are an integral part of thrombotic thrombocytopenic purpura and play a role in its pathogenesis, is raised.
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
August 2015,
Vox sanguinis,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
June 2003,
Transfusion,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
October 2002,
Transfusion,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
April 1985,
Annals of internal medicine,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
January 1981,
JAMA,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
February 1993,
American journal of hematology,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
January 1983,
Blood,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
October 1977,
JAMA,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
May 1978,
JAMA,
D Aderka, and
M Djaldetti, and
Y Shoenfeld, and
M Shaklai, and
M Santo, and
S Berliner, and
A Weinberger, and
J Pinkhas
June 1973,
Lancet (London, England),
